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Excessive Caffeine - Negative Effects on the Human Body

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Coffee is consumed throughout the world and yet most do not know the effects it causes to the body. With each cup drunk there are benefits and consequences that come with coffee consummation. Coffee has been known to have many health benefits. For starters, coffee has been shown to decrease the risk of type two diabetes mellitus. Type diabetes mellitus is a disease that has plagued people all over the world in which a person fails to produce enough insulin to keep his or her body at an overall equilibrium. Studies have shown that that drinking two or more cups of coffee a day can actually reduce the risk of acquiring type two diabetes mellitus (Coffee 7). Another study was performed in China. It was a study containing two thousands thirty two subjects, and a two stage sampling design was used to identify which residents of China that were to be chosen which were residents of ages forty or older (Lin 660). Blood tests were also done to make sure each subject had some form of type two diabetes mellitus whether it was a serious of mild case, and then they placed them in categories depending on the amount of coffee they drank each day (Lin 600). After obtaining the data, a t-test was performed to compare mean values since the data was only based on means and standard deviation, and log transformations were used for variables such as age, height, and weight since these variables can affect the severity of type two diabetes in the subjects, thus causing problems in the data (Lin 600-601). For example, a person that is obese and has type two diabetes mellitus would most likely have a more severe case than a person that diabetes but is not obese. Next, a Pearson's chi-test was performed to compare categorical data such as coffee drinkers with diabetes and non-coffee drinkers with diabetes (Lin 601). After performing the various statistical analyses, there was evidence that subjects with type two diabetes mellitus that drank coffee on a daily basis had a significantly lower severity than subjects that did not drink coffee. There was an inverse relationship between coffee drinking and diabetes mellitus (Lin 601). This means that the more coffee the person drinks, the lower the chances of that person getting type two diabetes mellitus. Coffee has also been shown to reduce that risk of developing various types of cancer. Studies have shown that women who drank coffee regularly reduced their risk of endometrial cancer by twenty percent, people who drank coffee regularly reduced their chance of pancreatic cancer, and people who drink an additional two cups of coffee a day can reduce their risk of liver cancer by forty-three percent (Coffee 7). Another study was performed in China in which the subjects had colorectal cancer and they were part of the Singapore Chinese Health Study (Peterson 22). Subjects were then placed in categories based on the amount of coffee each person drank so a chi-squared test was used since it was categorical data, and analysis of variance was used to compare the distribution of coffee consumption causing one-third to be placed in the category of drinking one cup a day, one-third to be placed in the category of drinking two or more cups a day, and one-third to be placed in the category of drinking none. (Peterson 22-23). After a year, blood samples were taken, and an analysis of covariance was used to examine the association between intake of coffee and level of plasma lipids since the level of plasma lipids showed the severity of the cancer (Peterson 23). After the statistical analyses, results showed that two or more cups of coffee a day showed a statistically significant reduction in colon cancer (Peterson 23). Another health benefit of coffee is the antioxidants that coffee contains. Antioxidants are very important for the human body since they prevent free radicals from causing oxidation, which causes cellular damage. "Coffee contains high levels of phenolic antioxidants called hydroxycinnamates, and, if consumed regularly throughout the day, coffee may represent a major source of exogenous antioxidants, (Ishizaka 1951). The caffeine in coffee can even have antioxidant properties (Ishizaka 1951). A study was performed in Japan with 9877 subjects in order to evaluate the effects of coffee on oxidant stress levels (Ishizaka 1952). Oxidant stress levels are measurements of the amount of oxidation on cells that is caused by free radicals. Subjects were placed in categories based on coffee intake, and blood samples were taken from each subject to observe oxidant stress levels in each subject (Ishizaka 1952). A chi-squared test was used to analyze the data, and the results showed that higher coffee intake decreased oxidant stress levels (Ishizaka 1952). The results were the same for drinkers of both caffeinated coffee and non-caffeinated coffee (Ishizaka 1956). This shows that it's not just the antioxidants from the caffeine that decreases oxidant stress levels, but also the antioxidants

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