How do you run away from things that are in your head? Mental illness sometimes called mental disorders are health condition that disturb a person’s mind, emotion, or behavior. So, it causes suffering or and inability to function properly in normal life. The disease was reported approximately 6000-5000 BC as trephined skull. Ancient Greece, Babylonian, Egyptian, and Chinese civilization believed that mental illness were possessed by evil spirits or witches. Nowadays the National Alliance on Mental Illness says that “one in four adults-approximately 61.5 million Americans-suffers or experiences mental illness in a given year”(1). There are a lot of types of mental illness, some can be threatening and some other can be harmless. Unfortunately there are negative attitude and disgrace known as stigma, toward mentally ill people. People always see those people as abnormal, horrific, or dangerous, and consequently labels them. Although mental illness mostly have no cure, it can be prevented from relapsing if individuals can understand their own unique patterns of behavior and causes. The causes of mental illness are many and consists of vary things depending on the individual and environment but still, some of the reasons are still unknown. These causes categorized to Biological, Psychological and Environmental factor. Most mental disorders are caused by a combination of factors that includes, genetics, substance abuses, and brain defects. For genetics factor, it always plays important role in the contribution to mental illness Psychopathologist never doubts that genes influences risk for mental illness. Speaking about genes, human gene is wonderful thing which contains every information to create living organism’s cells and passes genetic attribute to offspring. As for disease, it is no exception, sometimes mental illnesses can be inherited. Family risk studies in the article “Types and causes of mental disorders: Genetics” compared “the observed the frequency of occurrence of a mental illness in close relatives of the diagnosed patients and with it’s frequency in the general population”(9). And the result was close relatives like siblings, children, parents, or twins share 50% of their genetic information with the patient and rate of the illness was higher than expected which makes them highly possible or vulnerable subject of mental illness. Schizophrenia, for example, a chronic severe brain disorder results from poly pathogenic gene, those mentioned siblings of the diagnosed one have ten times higher